Molecular weight (DA)
52kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SSF1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation. [provided by RefSeq, Nov 2010],
Function
function:May have a role in cell growth.,miscellaneous:A putative trans-splicing which involves PPAN and P2RY11 gene regions produces a fusion protein.,similarity:Contains 1 Brix domain.,tissue specificity:Ubiquitous.,
Gene Name
PPAN BXDC3 SSF1
Protein name
Suppressor of SWI4 1 homolog (Ssf-1) (Brix domain-containing protein 3) (Peter Pan homolog)
Human protein sequence Database
Q9NQ55
Mouse protein sequence database
Q91YU8
Rat protein sequence database
Cellular localization
Nucleus, nucleolus .
Tissue expression
Widely expressed.
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