Molecular weight (DA)
69kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
S6A18 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The SLC6 family of proteins, which includes SLC6A18, act as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Apr 2010],
Function
similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:Abundantly expressed in kidney, but not in intestine.,
Protein name
Sodium-dependent neutral amino acid transporter B(0)AT3 (Sodium- and chloride-dependent transporter XTRP2) (Solute carrier family 6 member 18) (System B(0) neutral amino acid transporter AT3)
Human protein sequence Database
Q96N87
Mouse protein sequence database
O88576
Rat protein sequence database
Q62687
Cellular localization
Membrane ; Multi-pass membrane protein .
Tissue expression
Abundantly expressed in kidney, but not in intestine.
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