Molecular weight (DA)
44kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SPI2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The gene encodes a member of a family of proteins that acts as inhibitors of serine proteases. These proteins function in the regulation of a variety of physiological processes, including coagulation, fibrinolysis, development, malignancy, and inflammation. Expression of the encoded protein may be downregulated during pancreatic carcinogenesis. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013],
Function
similarity:Belongs to the serpin family.,tissue specificity:Expressed in pancreas and adipose tissues.,
Gene Name
SERPINI2 MEPI PI14
Protein name
Serpin I2 (Myoepithelium-derived serine protease inhibitor) (Pancpin) (Pancreas-specific protein TSA2004) (Peptidase inhibitor 14) (PI-14)
Human protein sequence Database
O75830
Mouse protein sequence database
Q9JK88
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Expressed in pancreas and adipose tissues.
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