Molecular weight (DA)
11kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 30-110
Specificity
S10AE Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the S100 protein family which contains an EF-hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828). [provided by RefSeq, Dec 2011],
Function
similarity:Belongs to the S-100 family.,similarity:Contains 2 EF-hand domains.,tissue specificity:Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.,
Gene Name
S100A14 S100A15
Protein name
Protein S100-A14 (S100 calcium-binding protein A14) (S114)
Human protein sequence Database
Q9HCY8
Mouse protein sequence database
Q9D2Q8
Rat protein sequence database
Cellular localization
Cytoplasm .
Tissue expression
Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.
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