Molecular weight (DA)
62kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 120-200
Specificity
TYSD1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013],
Function
function:Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and the specific processing of PTS1 proteins. May participate to a regulatory mechanism that control the peroxisomal beta-oxidation of fatty acids.,PTM:Processed into the 49 kDa and the 10 kDa forms upon import into the peroxisomes. The 49 kDa form probably corresponds to the mature enzyme, while the 10 kDa form may represent an inhibitory N-terminal fragment which prevents protease activity until it reaches the peroxisomes.,similarity:Belongs to the peptidase S1B family.,
Protein name
Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptid
Human protein sequence Database
Q2T9J0
Mouse protein sequence database
Q9DBA6
Rat protein sequence database
Cellular localization
Peroxisome .
Tissue expression
Brain,Lung,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车