Molecular weight (DA)
42kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 150-230
Specificity
P2RX4 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012],
Function
function:Receptor for ATP that acts as a ligand gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin.,online information:P2X receptor entry,similarity:Belongs to the P2X receptor family.,subunit:Homo- or heteropolymers.,
Protein name
P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor)
Fields
>>Calcium signaling pathway;>>Neuroactive ligand-receptor interaction
Human protein sequence Database
Q99571
Mouse protein sequence database
Q9JJX6
Rat protein sequence database
P51577
Cellular localization
Membrane ; Multi-pass membrane protein .
Tissue expression
Blood,Brain,Kidney,Liver,
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