Molecular weight (DA)
57kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 140-220
Specificity
NETO2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulating kainate receptor function. Expression of this gene may be a biomarker for proliferating infantile hemangiomas. A pseudogene of this gene is located on the long arm of chromosome 8. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],
Function
function:May play a role in the development and/or maintenance of neuronal circuitry.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 2 CUB domains.,
Gene Name
NETO2 BTCL2 UNQ1926/PRO4401
Protein name
Neuropilin and tolloid-like protein 2 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2)
Human protein sequence Database
Q8NC67
Mouse protein sequence database
Q8BNJ6
Rat protein sequence database
C6K2K4
Cellular localization
Membrane ; Single-pass type I membrane protein .
Tissue expression
Brain,Ovary,Skin,
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