Molecular weight (DA)
203kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 1120-1200
Specificity
MYO5B Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene, together with other proteins, may be involved in plasma membrane recycling. Mutations in this gene are associated with microvillous inclusion disease. [provided by RefSeq, Sep 2009],
Function
disease:Defects in MYO5B are a cause of microvillus inclusion disease (MVID) [MIM:251850]. MVID is characterized by onset of intractable life-threatening watery diarrhea during infancy. Two forms are recognized: early-onset MVID with diarrhea beginning in the neonatal period, and late-onset, with first symptoms appearing after 3 or 4 months of life.,similarity:Contains 1 dilute domain.,similarity:Contains 1 myosin head-like domain.,similarity:Contains 6 IQ domains.,subunit:Interacts with RAB11FIP2.,
Protein name
Unconventional myosin-Vb
Fields
>>Pathogenic Escherichia coli infection
Human protein sequence Database
Q9ULV0
Mouse protein sequence database
P21271
Rat protein sequence database
P70569
Cellular localization
Cytoplasm .
Tissue expression
Brain,Colon,
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