Molecular weight (DA)
83kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Specificity
MTSS1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
domain:The WH2 motif at the C-terminus binds to actin monomers.,function:May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.,similarity:Belongs to the MTSS1 family.,similarity:Contains 1 IMD (IRSp53/MIM homology) domain.,similarity:Contains 1 WH2 domain.,subunit:Binds to actin. Binds to the cytoplasmic domain of receptor protein tyrosine phosphatase delta.,tissue specificity:Expressed in many tissues, including spleen, thymus, prostate, testis, uterus, colon, and peripheral blood.,
Function
domain:The WH2 motif at the C-terminus binds to actin monomers.,function:May be related to cancer progression or tumor metastasis in a variety of organ sites, most likely through an interaction with the actin cytoskeleton.,similarity:Belongs to the MTSS1 family.,similarity:Contains 1 IMD (IRSp53/MIM homology) domain.,similarity:Contains 1 WH2 domain.,subunit:Binds to actin. Binds to the cytoplasmic domain of receptor protein tyrosine phosphatase delta.,tissue specificity:Expressed in many tissues, including spleen, thymus, prostate, testis, uterus, colon, and peripheral blood.,
Gene Name
MTSS1 KIAA0429 MIM
Protein name
Metastasis suppressor protein 1 (Metastasis suppressor YGL-1) (Missing in metastasis protein)
Human protein sequence Database
O43312
Mouse protein sequence database
Q8R1S4
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton.
Tissue expression
Expressed in many tissues, including spleen, thymus, prostate, testis, uterus, colon, and peripheral blood.
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