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MED10 Polyclonal Antibody

Polyclonal antibody

Specification

BYab-05712

  • 50UL $180 100UL $255
  • Delivery: In Stock

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Host
Reactiveness
Use
Molecular weight (DA)
14kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 40-120
Specificity
MED10 Polyclonal Antibody detects endogenous levels of protein.
Source
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Background
MED10 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008],
Function
function:Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.,similarity:Belongs to the Mediator complex subunit 10 family.,subunit:Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 su
Gene Name
MED10 L6 TRG17 TRG20
Protein name
Mediator of RNA polymerase II transcription subunit 10 (Mediator complex subunit 10) (Transformation-related gene 17 protein) (TRG-17) (Transformation-related gene 20 protein) (TRG-20)
Abbreviation
MED10
Other name
Fields
Human gene ID
84246
Human protein sequence Database
Q9BTT4
Mouse gene ID
Mouse protein sequence database
Q9CXU0
Rat gene ID
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Placenta,
Storage
-20°C/1 year

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MED10 Polyclonal Antibody

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