Molecular weight (DA)
85kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
SIX4 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the homeobox family, subfamily SIX. The drosophila homolog is a nuclear homeoprotein required for eye development. Studies in mouse show that this gene product functions as a transcription factor, and may have a role in the differentiation or maturation of neuronal cells. [provided by RefSeq, May 2010],
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the SIX/Sine oculis homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,
Protein name
Homeobox protein SIX4 (Sine oculis homeobox homolog 4)
Fields
>>Transcriptional misregulation in cancer
Human protein sequence Database
Q9UIU6
Mouse protein sequence database
Q61321
Rat protein sequence database
Cellular localization
Nucleus . Cytoplasm .
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