Molecular weight (DA)
111kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
FNBP4 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
domain:These WW domains interact with Arg/Gly-rich-flanked Pro-rich domains found in several WW domain-binding proteins (WBPs). The N-terminal WW domain has the greater ligand-binding ability.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 WW domains.,subunit:Binds FMN1. Interacts with the Arg/Gly-rich-flanked Pro-rich of KHDRBS1/SAM68. Arginine methylation in these regions has no effect on this binding.,
Function
domain:These WW domains interact with Arg/Gly-rich-flanked Pro-rich domains found in several WW domain-binding proteins (WBPs). The N-terminal WW domain has the greater ligand-binding ability.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 WW domains.,subunit:Binds FMN1. Interacts with the Arg/Gly-rich-flanked Pro-rich of KHDRBS1/SAM68. Arginine methylation in these regions has no effect on this binding.,
Gene Name
FNBP4 FBP30 KIAA1014
Protein name
Formin-binding protein 4 (Formin-binding protein 30)
Human protein sequence Database
Q8N3X1
Mouse protein sequence database
Q6ZQ03
Rat protein sequence database
Cellular localization
nucleoplasm,
Tissue expression
Highly expressed in the eye.
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