Molecular weight (DA)
101kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
ETAA1 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,tissue specificity:Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.,
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,tissue specificity:Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.,
Protein name
Ewing's tumor-associated antigen 1 (Ewing's tumor-associated antigen 16)
Human protein sequence Database
Q9NY74
Mouse protein sequence database
Q5SVT3
Rat protein sequence database
Cellular localization
Nucleus . Localizes at sites of DNA damage following replication stress (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex (PubMed:27601467, PubMed:27723720). .
Tissue expression
Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.
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