Molecular weight (DA)
32kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
3MG Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
alternative products:Experimental confirmation may be lacking for some isoforms,catalytic activity:Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.,function:Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.,similarity:Belongs to the DNA glycosylase MPG family.,subunit:Binds MBD1.,
Function
alternative products:Experimental confirmation may be lacking for some isoforms,catalytic activity:Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.,function:Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.,similarity:Belongs to the DNA glycosylase MPG family.,subunit:Binds MBD1.,
Gene Name
MPG AAG ANPG MID1
Protein name
DNA-3-methyladenine glycosylase (EC 3.2.2.21) (3-alkyladenine DNA glycosylase) (3-methyladenine DNA glycosidase) (ADPG) (N-methylpurine-DNA glycosylase)
Fields
>>Base excision repair
Human protein sequence Database
P29372
Mouse protein sequence database
Q04841
Rat protein sequence database
P23571
Cellular localization
Cytoplasm . Mitochondrion matrix, mitochondrion nucleoid . Nucleus .
Tissue expression
Epithelium,Liver,Pancreas,
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