Molecular weight (DA)
52kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CNDP2 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
CNDP dipeptidase 2 (metallopeptidase M20 family)(CNDP2) Homo sapiens CNDP2, also known as tissue carnosinase and peptidase A (EC 3.4.13.18), is a nonspecific dipeptidase rather than a selective carnosinase (Teufel et al., 2003 [PubMed 12473676]).[supplied by OMIM, Mar 2008],
Function
cofactor:Binds 2 zinc ions per subunit.,similarity:Belongs to the peptidase M20A family.,
Gene Name
CNDP2 CN2 CPGL PEPA
Protein name
Cytosolic non-specific dipeptidase (EC 3.4.13.18) (CNDP dipeptidase 2) (Glutamate carboxypeptidase-like protein 1) (Peptidase A)
Fields
>>Arginine and proline metabolism;>>Histidine metabolism;>>beta-Alanine metabolism;>>Metabolic pathways
Human protein sequence Database
Q96KP4
Mouse protein sequence database
Q9D1A2
Rat protein sequence database
Q6Q0N1
Cellular localization
Cytoplasm .
Tissue expression
[Isoform 1]: Ubiquitously expressed with higher levels in kidney and liver (at protein level). Expressed in peripheral blood leukocytes (PubMed:12473676). Expressed in gastric mucosa and down-regulated in gastric cancer mucosal tissues (at protein level) (PubMed:24395568). ; [Isoform 2]: Broadly expressed in fetal tissues. Expressed in adult liver and placenta.
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