Molecular weight (DA)
29kD
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
CEAM7 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal cancer. Additionally, lower expression levels of this gene may be predictive of rectal cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015],
Function
similarity:Belongs to the immunoglobulin superfamily. CEA family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,tissue specificity:Strongly down-regulated in colonic adenocarcinomas.,
Protein name
Carcinoembryonic antigen-related cell adhesion molecule 7 (Carcinoembryonic antigen CGM2)
Human protein sequence Database
Q14002
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cell membrane ; Lipid-anchor, GPI-anchor . Apical cell membrane . Localized to the apical glycocalyx surface. .
Tissue expression
Expressed in columnar epithelial cells of the colon (at protein level) (PubMed:10436421). Strongly down-regulated in colonic adenocarcinomas.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车