Molecular weight (DA)
55kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 150-230
Specificity
ANGP4 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The mechanism by which they contribute to angiogenesis is thought to involve regulation of endothelial cell interactions with supporting perivascular cells. The protein encoded by this gene functions as an agonist and is an angiopoietin. [provided by RefSeq, Jul 2008],
Function
caution:Was originally (PubMed:10218486) called angiopoietin-3.,function:Binds to tyrosine-protein kinase receptor TIE2 and activates it.,similarity:Contains 1 fibrinogen C-terminal domain.,tissue specificity:Highly expressed in the lung with much lower levels found in other tissues.,
Gene Name
ANGPT4 ANG3 ANG4
Protein name
Angiopoietin-4 (ANG-4) (Angiopoietin-3) (ANG-3)
Fields
>>MAPK signaling pathway;>>Ras signaling pathway;>>Rap1 signaling pathway;>>HIF-1 signaling pathway;>>PI3K-Akt signaling pathway
Human protein sequence Database
Q9Y264
Mouse protein sequence database
Q9WVH6
Rat protein sequence database
Cellular localization
Secreted .
Tissue expression
Highly expressed in the lung with much lower levels found in other tissues.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车