Molecular weight (DA)
33kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 210-290
Specificity
RM02 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Function
similarity:Belongs to the ribosomal protein L2P family.,
Protein name
39S ribosomal protein L2, mitochondrial (L2mt) (MRP-L2)
Human protein sequence Database
Q5T653
Mouse protein sequence database
Q9D773
Rat protein sequence database
Q498T4
Cellular localization
Mitochondrion .
Tissue expression
Ovary,Skin,
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