Molecular weight (DA)
68kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 340-420
Specificity
K1C9 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
keratin 9(KRT9) Homo sapiens This gene encodes the type I keratin 9, an intermediate filament chain expressed only in the terminally differentiated epidermis of palms and soles. Mutations in this gene cause epidermolytic palmoplantar keratoderma. [provided by RefSeq, Jul 2008],
Function
caution:Was originally (PubMed:2140676) thought to be a 60 kDa chain of placental scatter protein.,disease:Defects in KRT9 are a cause of palmoplantar keratoderma epidermolytic (EPPK) [MIM:144200]; also abbreviated EHPPK. EPPK is a dermatological disorder characterized by diffuse thickening of the epidermis on the entire surface of palms and soles sharply bordered with erythematous margins.,disease:Knuckle pads are sometimes associated with EPPK [MIM:149100]. Knuckle pads consist of an autosomal dominant trait, in which thick pads of skin appear over the proximal phalangeal joints.,function:May serve an important special function either in the mature palmar and plantar skin tissue or in the morphogenetic program of the formation of these tissues. Plays a role in keratin filament assembly.,induction:Induced by intrinsic regulatory mechanisms and by extrinsic signals from a subset of derma
Protein name
Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)
Fields
>>Estrogen signaling pathway;>>Staphylococcus aureus infection
Human protein sequence Database
P35527
Mouse protein sequence database
Q6RHW0
Rat protein sequence database
Q8CIS9
Cellular localization
extracellular space,nucleus,intermediate filament,membrane,extracellular exosome,
Tissue expression
Expressed in the terminally differentiated epidermis of palms and soles.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车