Molecular weight (DA)
33kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Specificity
CDK3 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
cyclin dependent kinase 3(CDK3) Homo sapiens This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. [provided by RefSeq, Jul 2008],
Function
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Probably involved in the control of the cell cycle. Interacts with a yet unknown type of cyclin. Can phosphorylate histone H1.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CABLES1.,
Protein name
Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)
Human protein sequence Database
Q00526
Mouse protein sequence database
Q80YP0
Rat protein sequence database
Tissue expression
Expressed in cancer cell lines and glioblastoma tissue.
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