Molecular weight (DA)
185kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 1310-1390
Specificity
LMO7 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known. [provided by RefSeq, Jan 2009],
Function
sequence caution:Intron retention.,similarity:Contains 1 CH (calponin-homology) domain.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 1 PDZ (DHR) domain.,tissue specificity:Widely expressed. Isoform 2 and isoform 4 are predominantly expressed in brain.,
Gene Name
LMO7 FBX20 FBXO20 KIAA0858
Protein name
LIM domain only protein 7 (LMO-7) (F-box only protein 20) (LOMP)
Fields
>>Adherens junction
Human protein sequence Database
Q8WWI1
Mouse protein sequence database
Rat protein sequence database
Cellular localization
ubiquitin ligase complex,nucleus,cytoplasm,cell-cell adherens junction,focal adhesion,integral component of membrane,apical plasma membrane,
Tissue expression
Widely expressed. Isoform 2 and isoform 4 are predominantly expressed in brain.
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