Molecular weight (DA)
25kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 150-230
Specificity
RN141 Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
ring finger protein 141(RNF141) Homo sapiens The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-DNA and protein-protein interactions. Abundant expression of this gene was found in the testicular tissue of fertile men, but was not detected in azoospermic patients. Studies of the mouse counterpart suggest that this gene may function as a testis specific transcription factor during spermatogenesis. [provided by RefSeq, Jul 2008],
Function
function:May be involved in spermatogenesis.,similarity:Contains 1 RING-type zinc finger.,tissue specificity:Isoform 1 is testis-specific. Isoform 2 is expressed in heart, brain, skeletal muscle, kidney and pancreas. Isoform 1 is not expressed in fetus or in azoospermic patients.,
Protein name
RING finger protein 141 (Zinc finger protein 230)
Human protein sequence Database
Q8WVD5
Mouse protein sequence database
Q99MB7
Rat protein sequence database
Q6IV57
Cellular localization
Membrane ; Lipid-anchor .
Tissue expression
Isoform 1 is testis-specific. Isoform 2 is expressed in heart, brain, skeletal muscle, kidney and pancreas. Isoform 1 is not expressed in fetus or in azoospermic patients.
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