Molecular weight (DA)
47kD
Immunogen
Synthesized peptide derived from human protein . at AA range: 100-180
Specificity
NOCT Polyclonal Antibody detects endogenous levels of protein.
Formulation
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 ELISA 1:5000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
nocturnin(NOCT) Homo sapiens The protein encoded by this gene is highly similar to Nocturnin, a gene identified as a circadian clock regulated gene in Xenopus laevis. This protein and Nocturnin protein share similarity with the C-terminal domain of a yeast transcription factor, carbon catabolite repression 4 (CCR4). The mRNA abundance of a similar gene in mouse has been shown to exhibit circadian rhythmicity, which suggests a role for this protein in clock function or as a circadian clock effector. [provided by RefSeq, Jul 2008],
Function
function:Component of the circadian clock or downstream effector of clock function. Exhibits a high amplitude circadian rhythm with maximal levels in early evening. In constant darkness or constant light, the amplitude of the rhythm decreases.,similarity:Belongs to the CCR4/nocturin family.,
Gene Name
CCRN4L CCR4 NOC
Protein name
Nocturnin (CCR4 protein homolog)
Human protein sequence Database
Q9UK39
Mouse protein sequence database
O35710
Rat protein sequence database
Q9ET55
Cellular localization
Cytoplasm . Nucleus . Cytoplasm, perinuclear region . Mitochondrion .
Tissue expression
Adipose tissue. Expression is higher in subcutaneous adipose tissue as compared to visceral adipose tissue.
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