Molecular weight (DA)
37kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SFXN4. AA range:1-50
Specificity
Sideroflexin-4 Polyclonal Antibody detects endogenous levels of Sideroflexin-4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the sideroflexin family. The encoded protein is a transmembrane protein of the inner mitochondrial membrane, and is required for mitochondrial respiratory homeostasis and erythropoiesis. Mutations in this gene are associated with mitochondriopathy and macrocytic anemia. Alternatively spliced transcript variants have been found in this gene. [provided by RefSeq, Jan 2014],
Function
function:Potential iron transporter.,similarity:Belongs to the sideroflexin family.,
Protein name
Sideroflexin-4
Abbreviation
Sideroflexin-4
Other name
SFXN4; BCRM1; Sideroflexin-4; Breast cancer resistance marker 1
Human protein sequence Database
Q6P4A7
Mouse protein sequence database
Q925N1
Rat protein sequence database
Cellular localization
Mitochondrion inner membrane ; Multi-pass membrane protein .
Tissue expression
Mammary tumor,Placenta,Tongue,
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