Molecular weight (DA)
45kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SERPINB4. AA range:261-310
Specificity
SCCA2 Polyclonal Antibody detects endogenous levels of SCCA2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:May act as a protease inhibitor to modulate the host immune response against tumor cells.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,subcellular location:Seems to also be secreted in plasma by cancerous cells but at a low level.,tissue specificity:Squamous cells.,
Function
function:May act as a protease inhibitor to modulate the host immune response against tumor cells.,similarity:Belongs to the serpin family.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,subcellular location:Seems to also be secreted in plasma by cancerous cells but at a low level.,tissue specificity:Squamous cells.,
Other name
SERPINB4; PI11; SCCA2; Serpin B4; Leupin; Peptidase inhibitor 11; PI-11; Squamous cell carcinoma antigen 2; SCCA-2
Human protein sequence Database
P48594
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm . Seems to also be secreted in plasma by cancerous cells but at a low level.
Tissue expression
Squamous cells.