Molecular weight (DA)
20kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RPL28. AA range:41-90
Specificity
Ribosomal Protein L28 Polyclonal Antibody detects endogenous levels of Ribosomal Protein L28 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L28E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Oct 2008],
Function
similarity:Belongs to the ribosomal protein L28e family.,
Protein name
60S ribosomal protein L28
Abbreviation
Ribosomal Protein L28
Other name
RPL28; 60S ribosomal protein L28
Fields
>>Ribosome;>>Coronavirus disease - COVID-19
Human protein sequence Database
P46779
Mouse protein sequence database
P41105
Rat protein sequence database
P17702
Cellular localization
cytoplasm,cytosol,ribosome,membrane,cytosolic large ribosomal subunit,dendrite,cytoplasmic ribonucleoprotein granule,cell body,extracellular exosome,
Tissue expression
B-cell,Cerebellum,Colon,Hepatoma,Kidney,Ovarian carcinoma,Spleen,Uterus,
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