Molecular weight (DA)
26kD
Immunogen
The antiserum was produced against synthesized peptide derived from human RPL14. AA range:71-120
Specificity
Ribosomal Protein L14 Polyclonal Antibody detects endogenous levels of Ribosomal Protein L14 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Function
polymorphism:The poly-Ala stretch is highly polymorphic.,similarity:Belongs to the ribosomal protein L14e family.,
Protein name
60S ribosomal protein L14
Abbreviation
Ribosomal Protein L14
Other name
RPL14; 60S ribosomal protein L14; CAG-ISL 7
Fields
>>Ribosome;>>Coronavirus disease - COVID-19
Human protein sequence Database
P50914
Mouse protein sequence database
Q9CR57
Rat protein sequence database
Q63507
Cellular localization
cytoplasm,cytosol,ribosome,cell-cell adherens junction,membrane,cytosolic large ribosomal subunit,extracellular exosome,
Tissue expression
Brain,Cervix carcinoma,Dermoid cancer,Epithelium,Kidney,Muscle,Ovary,Pancreas,Skin,
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