Molecular weight (DA)
49kD
Immunogen
The antiserum was produced against synthesized peptide derived from human AGFG2. AA range:91-140
Specificity
Rabr Polyclonal Antibody detects endogenous levels of Rabr protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
ArfGAP with FG repeats 2(AGFG2) Homo sapiens This gene is a member of the HIV-1 Rev binding protein (HRB) family and encodes a protein with one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. This protein interacts with Eps15 homology (EH) domains and plays a role in the Rev export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Feb 2013],
Function
domain:Contains FG repeats and 4 N-P-F repeats.,similarity:Contains 1 Arf-GAP domain.,subunit:Interacts with EPS15R.,
Protein name
Arf-GAP domain and FG repeat-containing protein 2
Other name
AGFG2; HRBL; RABR; Arf-GAP domain and FG repeat-containing protein 2; HIV-1 Rev-binding protein-like protein; Rev/Rex activation domain-binding protein related; RAB-R
Human protein sequence Database
O95081
Mouse protein sequence database
Q80WC7
Rat protein sequence database
Cellular localization
membrane,
Tissue expression
Brain,Kidney,Placenta,
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