Immunogen
The antiserum was produced against synthesized peptide derived from human NOM1. AA range:661-710
Specificity
NOM1 Polyclonal Antibody detects endogenous levels of NOM1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Proteins that contain MIF4G (middle of eIF4G (MIM 600495)) and/or MA3 domains, such as NOM1, function in protein translation. These domains include binding sites for members of the EIF4A family of ATP-dependent DEAD box RNA helicases (see EIF4A1; MIM 602641) (Simmons et al., 2005 [PubMed 15715967]).[supplied by OMIM, Mar 2008],
Function
similarity:Belongs to the CWC22 family.,similarity:Contains 1 MI domain.,similarity:Contains 1 MIF4G domain.,subunit:May interact with EIF4A1, EIF4A2 and EIF4A3.,tissue specificity:Expressed in heart and skeletal muscle.,
Protein name
Nucleolar MIF4G domain-containing protein 1
Other name
NOM1; C7orf3; Nucleolar MIF4G domain-containing protein 1; SGD1 homolog
Human protein sequence Database
Q5C9Z4
Mouse protein sequence database
Q3UFM5
Rat protein sequence database
Cellular localization
Nucleus, nucleolus .
Tissue expression
Expressed in heart and skeletal muscle.
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