Molecular weight (DA)
160kD
Immunogen
The antiserum was produced against synthesized peptide derived from human NBEAL1. AA range:566-615
Specificity
NBEAL1 Polyclonal Antibody detects endogenous levels of NBEAL1 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
sequence caution:Translated as stop.,similarity:Belongs to the WD repeat neurobeachin family.,similarity:Contains 1 BEACH domain.,similarity:Contains 2 WD repeats.,tissue specificity:Highly expressed in brain, kidney, prostate and testis. Weakly expressed in ovary, small intestine, colon and peripheral blood leukocytes. May be correlative to several tumors, such as ovary serous adenocarcinoma and metastasis mammary gland carcinoma breast.,
Function
sequence caution:Translated as stop.,similarity:Belongs to the WD repeat neurobeachin family.,similarity:Contains 1 BEACH domain.,similarity:Contains 2 WD repeats.,tissue specificity:Highly expressed in brain, kidney, prostate and testis. Weakly expressed in ovary, small intestine, colon and peripheral blood leukocytes. May be correlative to several tumors, such as ovary serous adenocarcinoma and metastasis mammary gland carcinoma breast.,
Protein name
Neurobeachin-like protein 1
Other name
NBEAL1; ALS2CR16; ALS2CR17; Neurobeachin-like protein 1; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein
Human protein sequence Database
Q6ZS30
Mouse protein sequence database
Rat protein sequence database
Cellular localization
endomembrane system,extrinsic component of membrane,
Tissue expression
Highly expressed in brain, kidney, prostate and testis. Weakly expressed in ovary, small intestine, colon and peripheral blood leukocytes. May be correlative to several tumors, such as ovary serous adenocarcinoma and metastasis mammary gland carcinoma breast.