Molecular weight (DA)
15kD
Immunogen
The antiserum was produced against synthesized peptide derived from human MRPS36. AA range:4-53
Specificity
MRP-S36 Polyclonal Antibody detects endogenous levels of MRP-S36 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. [provided by RefSeq, Jul 2008],
Function
subunit:Component of the mitochondrial ribosome small subunit (28S) which comprises a 12S rRNA and about 30 distinct proteins.,
Protein name
28S ribosomal protein S36 mitochondrial
Other name
MRPS36; DC47; 28S ribosomal protein S36; mitochondrial; MRP-S36; S36mt
Human protein sequence Database
P82909
Mouse protein sequence database
Q9CQX8
Rat protein sequence database
Cellular localization
Mitochondrion .
Tissue expression
Dendritic cell,Kidney,Prostate,
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