Molecular weight (DA)
24kD
Immunogen
The antiserum was produced against synthesized peptide derived from human HSPB2. AA range:121-170
Specificity
HSP β2 Polyclonal Antibody detects endogenous levels of HSP β2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The protein is expressed preferentially in the heart and skeletal muscle. This protein regulates Myotonic Dystrophy Protein Kinase, which plays an important role in maintenance of muscle structure and function. [provided by RefSeq, Dec 2012],
Function
similarity:Belongs to the small heat shock protein (HSP20) family.,subunit:Associates specifically with myotonic dystrophy protein kinase (DMPK).,tissue specificity:Expressed preferentially in skeletal muscle and heart but not in the lens.,
Protein name
Heat shock protein beta-2
Other name
HSPB2; Heat shock protein beta-2; HspB2; DMPK-binding protein; MKBP
Fields
>>Proteoglycans in cancer
Human protein sequence Database
Q16082
Mouse protein sequence database
Q99PR8
Rat protein sequence database
O35878
Cellular localization
Cytoplasm . Nucleus . Localizes to nuclear foci.
Tissue expression
Expressed preferentially in skeletal muscle and heart but not in the lens.
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