Molecular weight (DA)
60kD
Immunogen
Synthesized peptide derived from the C-terminal region of human CPN reg.
Specificity
CPN reg Polyclonal Antibody detects endogenous levels of CPN reg protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.,PTM:Whether or not any Cys residues participate in intrachain bonds is unknown, but they do not form interchain disulfide bonds with the 50 kDa catalytic subunit.,similarity:Contains 13 LRR (leucine-rich) repeats.,subunit:Tetramer of two catalytic chains and two glycosylated inactive chains.,
Function
function:The 83 kDa subunit binds and stabilizes the catalytic subunit at 37 degrees Celsius and keeps it in circulation. Under some circumstances it may be an allosteric modifier of the catalytic subunit.,PTM:Whether or not any Cys residues participate in intrachain bonds is unknown, but they do not form interchain disulfide bonds with the 50 kDa catalytic subunit.,similarity:Contains 13 LRR (leucine-rich) repeats.,subunit:Tetramer of two catalytic chains and two glycosylated inactive chains.,
Protein name
Carboxypeptidase N subunit 2
Other name
CPN2; ACBP; Carboxypeptidase N subunit 2; Carboxypeptidase N 83 kDa chain; Carboxypeptidase N large subunit; Carboxypeptidase N polypeptide 2; Carboxypeptidase N regulatory subunit
Human protein sequence Database
P22792
Mouse protein sequence database
Q9DBB9
Rat protein sequence database
Cellular localization
Secreted.
Tissue expression
Hepatoblastoma,Plasma,
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