Molecular weight (DA)
64kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ARSI. AA range:311-360
Specificity
Arylsulfatase I Polyclonal Antibody detects endogenous levels of Arylsulfatase I protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that belongs to a large family of sulfatases that hydrolyze sulfate esters and sulfamates. Members of this family play a role in several cellular processes, including hormone synthesis, cell signaling in development and degradation of macromolecules. The protein encoded by this gene is thought to be secreted, and to function in extracellular space. [provided by RefSeq, Jul 2016],
Function
cofactor:Binds 1 calcium ion per subunit.,PTM:The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.,similarity:Belongs to the sulfatase family.,
Protein name
Arylsulfatase I
Abbreviation
Arylsulfatase I
Other name
ARSI; Arylsulfatase I; ASI
Human protein sequence Database
Q5FYB1
Mouse protein sequence database
Q32KI9
Rat protein sequence database
Cellular localization
Secreted . Endoplasmic reticulum . Localized in the intracellular granular structures.
Tissue expression
Expressed in placenta, in embryonic stem cells, fetal eyes and lens.
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