Immunogen
The antiserum was produced against synthesized peptide derived from human SPTBN5. AA range:481-530
Specificity
Spectrin β V Polyclonal Antibody detects endogenous levels of Spectrin β V protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
similarity:Belongs to the spectrin family.,similarity:Contains 1 PH domain.,similarity:Contains 2 CH (calponin-homology) domains.,similarity:Contains 31 spectrin repeats.,subcellular location:Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.,subunit:Probably associates with an alpha chain.,tissue specificity:Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.,
Function
similarity:Belongs to the spectrin family.,similarity:Contains 1 PH domain.,similarity:Contains 2 CH (calponin-homology) domains.,similarity:Contains 31 spectrin repeats.,subcellular location:Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.,subunit:Probably associates with an alpha chain.,tissue specificity:Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.,
Protein name
Spectrin beta chain non-erythrocytic 5
Abbreviation
Spectrin β V
Other name
SPTBN5; BSPECV; HUBSPECV; HUSPECV; Spectrin beta chain; non-erythrocytic 5; Beta-V spectrin
Human protein sequence Database
Q9NRC6
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Cytoplasm, cytoskeleton. Detected prominently in the outer segments of photoreceptor rods and cones and in the basolateral membrane and cytosol of gastric epithelial cells.
Tissue expression
Expressed at very low levels in many tissues, with strongest expression in cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder, and heart.