Molecular weight (DA)
11kD
Immunogen
The antiserum was produced against synthesized peptide derived from human S-100A10. AA range:3-52
Specificity
S-100A10 Polyclonal Antibody detects endogenous levels of S-100A10 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in exocytosis and endocytosis. [provided by RefSeq, Jul 2008],
Function
function:Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.,miscellaneous:Does not appear to bind calcium. Contains 2 ancestral calcium site related to EF-hand domains that have lost their ability to bind calcium.,similarity:Belongs to the S-100 family.,subunit:Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36. Interacts with SCN10A.,
Protein name
Protein S100-A10
Other name
S100A10; ANX2LG; CAL1L; CLP11; Protein S100-A10; Calpactin I light chain; Calpactin-1 light chain; Cellular ligand of annexin II; S100 calcium-binding protein A10; p10 protein; p11
Fields
>>Salmonella infection
Human protein sequence Database
P60903
Mouse protein sequence database
P08207
Rat protein sequence database
P05943
Cellular localization
integral component of membrane,extrinsic component of plasma membrane,membrane raft,extracellular exosome,
Tissue expression
Brain,Keratinocyte,
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