Molecular weight (DA)
125kD
Immunogen
Synthesized peptide derived from the N-terminal region of human USP43.
Specificity
USP43 Polyclonal Antibody detects endogenous levels of USP43 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in brain, aorta and lung at low levels.,
Function
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins.,similarity:Belongs to the peptidase C19 family.,tissue specificity:Expressed in brain, aorta and lung at low levels.,
Protein name
Ubiquitin carboxyl-terminal hydrolase 43
Other name
USP43; Ubiquitin carboxyl-terminal hydrolase 43; Deubiquitinating enzyme 43; Ubiquitin thioesterase 43; Ubiquitin-specific-processing protease 43
Human protein sequence Database
Q70EL4
Mouse protein sequence database
Q8BUM9
Rat protein sequence database
Cellular localization
nucleoplasm,
Tissue expression
Expressed in brain, aorta and lung at low levels.
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