Molecular weight (DA)
120kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ACAD10. AA range:231-280
Specificity
ACAD-10 Polyclonal Antibody detects endogenous levels of ACAD-10 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000 IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
acyl-CoA dehydrogenase family member 10(ACAD10) Homo sapiens This gene encodes a member of the acyl-CoA dehydrogenase family of enzymes (ACADs), which participate in the beta-oxidation of fatty acids in mitochondria. The encoded enzyme contains a hydrolase domain at the N-terminal portion, a serine/threonine protein kinase catlytic domain in the central region, and a conserved ACAD domain at the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Nov 2008],
Function
similarity:Belongs to the acyl-CoA dehydrogenase family.,tissue specificity:Widely expressed with higher expression in liver, kidney, pancreas and spleen.,
Protein name
Acyl-CoA dehydrogenase family member 10
Other name
ACAD10; Acyl-CoA dehydrogenase family member 10; ACAD-10
Human protein sequence Database
Q6JQN1
Mouse protein sequence database
Q8K370
Rat protein sequence database
Cellular localization
mitochondrion,mitochondrial matrix,
Tissue expression
Widely expressed with highest expression in fetal brain, followed by heart, muscle, kidney and adult brain. Expression levels varying from isoform to isoform.
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