Molecular weight (DA)
24kD
Immunogen
The antiserum was produced against synthesized peptide derived from human EF-1beta. AA range:83-132
Specificity
EF-1β Polyclonal Antibody detects endogenous levels of EF-1β protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a translation elongation factor. The protein is a guanine nucleotide exchange factor involved in the transfer of aminoacylated tRNAs to the ribosome. Alternative splicing results in three transcript variants which differ only in the 5' UTR. [provided by RefSeq, Jul 2008],
Function
function:EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.,PTM:Phosphorylation affects the GDP/GTP exchange rate.,similarity:Belongs to the EF-1-beta/EF-1-delta family.,similarity:Contains 1 GST C-terminal domain.,subunit:EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.,
Protein name
Elongation factor 1-beta
Other name
EEF1B2; EEF1B; EF1B; Elongation factor 1-beta; EF-1-beta
Human protein sequence Database
P24534
Mouse protein sequence database
O70251
Rat protein sequence database
Cellular localization
nucleus,cytoplasm,endoplasmic reticulum,cytosol,eukaryotic translation elongation factor 1 complex,
Tissue expression
Brain,Epithelium,Eye,Fetal brain cortex,Keratinocyt
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