Molecular weight (DA)
80kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ZNF420. AA range:301-350
Specificity
ZNF420 Polyclonal Antibody detects endogenous levels of ZNF420 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
zinc finger protein 420(ZNF420) Homo sapiens The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016],
Function
function:May be involved in transcriptional regulation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 KRAB domain.,similarity:Contains 19 C2H2-type zinc fingers.,
Protein name
Zinc finger protein 420
Other name
ZNF420; Zinc finger protein 420
Fields
>>Herpes simplex virus 1 infection
Human protein sequence Database
Q8TAQ5
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus .
Tissue expression
Muscle,Placenta,Testis,
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车