Molecular weight (DA)
68kD
Immunogen
The antiserum was produced against synthesized peptide derived from human TBX18. AA range:121-170
Specificity
TBX18 Polyclonal Antibody detects endogenous levels of TBX18 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
T-box 18(TBX18) Homo sapiens This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012],
Function
function:Probable transcriptional regulator involved in developmental processes.,similarity:Contains 1 T-box DNA-binding domain.,
Protein name
T-box transcription factor TBX18
Other name
TBX18; T-box transcription factor TBX18; T-box protein 18
Human protein sequence Database
O95935
Mouse protein sequence database
Q9EPZ6
Rat protein sequence database
Cellular localization
Nucleus .
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