Molecular weight (DA)
54kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SFRS11. AA range:211-260
Specificity
SFRS11 Polyclonal Antibody detects endogenous levels of SFRS11 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12.[provided by RefSeq, Sep 2010],
Function
function:May function in pre-mRNA splicing.,similarity:Belongs to the splicing factor SR family.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Colocalizes with spliceosome components.,subunit:Interacts with PUF60.,
Protein name
Serine/arginine-rich splicing factor 11
Other name
SRSF11; SFRS11; Serine/arginine-rich splicing factor 11; Arginine-rich 54 kDa nuclear protein; p54; Splicing factor; arginine/serine-rich 11
Human protein sequence Database
Q05519
Mouse protein sequence database
Rat protein sequence database
Cellular localization
Nucleus. Colocalizes with spliceosome components.
Tissue expression
Colon endothel,Epithelium,Fetal brain,Hepatoma,Human fetal
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