Molecular weight (DA)
46kD
Immunogen
The antiserum was produced against synthesized peptide derived from human POLDIP3. AA range:348-397
Specificity
POLDIP3 Polyclonal Antibody detects endogenous levels of POLDIP3 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes an RRM (RNA recognition motif)-containing protein that participates in the regulation of translation by recruiting ribosomal protein S6 kinase beta-1 to mRNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Interacts with POLD2.,
Protein name
Polymerase delta-interacting protein 3
Other name
POLDIP3; KIAA1649; PDIP46; Polymerase delta-interacting protein 3; 46 kDa DNA polymerase delta interaction protein; p46; S6K1 Aly/REF-like target; SKAR
Human protein sequence Database
Q9BY77
Mouse protein sequence database
Q8BG81
Rat protein sequence database
Cellular localization
Nucleus. Nucleus speckle. Cytoplasm. Nucleocytoplasmic shuttling protein.
Tissue expression
Brain,Epithelium,Ovarian carcinoma,Placenta,Skin,Testis,
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