Molecular weight (DA)
47kD
Immunogen
The antiserum was produced against synthesized peptide derived from human LUC7L2. AA range:129-178
Specificity
LUC7L2 Polyclonal Antibody detects endogenous levels of LUC7L2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/40000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],
Function
function:May bind to RNA via its Arg/Ser-rich domain.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the Luc7 family.,similarity:Contains 1 C2H2-type zinc finger.,
Protein name
Putative RNA-binding protein Luc7-like 2
Other name
LUC7L2; CGI-59; CGI-74; Putative RNA-binding protein Luc7-like 2
Human protein sequence Database
Q9Y383
Mouse protein sequence database
Q7TNC4
Rat protein sequence database
Cellular localization
Nucleus speckle . Nucleus, nucleoplasm . Colocalizes with SCNM1 and SNRNP70 in nuclear speckles. .
Tissue expression
Brain,Epithelium,Skin,Uterus,
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