Molecular weight (DA)
24kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ID4. AA range:1-50
Specificity
Id4 Polyclonal Antibody detects endogenous levels of Id4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the inhibitor of DNA binding (ID) protein family. These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity. Consequently, the activity of the encoded protein depends on the protein binding partner. [provided by RefSeq, Dec 2011],
Function
function:ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Heterodimer with other HLH proteins.,
Protein name
DNA-binding protein inhibitor ID-4
Other name
ID4; BHLHB27; DNA-binding protein inhibitor ID-4; Class B basic helix-loop-helix protein 27; bHLHb27; Inhibitor of DNA binding 4
Fields
>>TGF-beta signaling pathway;>>Signaling pathways regulating pluripotency of stem cells
Human protein sequence Database
P47928
Mouse protein sequence database
P41139
Rat protein sequence database
Cellular localization
Nucleus.
Tissue expression
Abdominal adipose tissue,Uterus,
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