Molecular weight (DA)
85kD
Immunogen
The antiserum was produced against synthesized peptide derived from human HSF2. AA range:401-450
Specificity
HSF2 Polyclonal Antibody detects endogenous levels of HSF2 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
heat shock transcription factor 2(HSF2) Homo sapiens The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],
Function
function:DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable to bind to the HSE unless the cells are heat shocked.,similarity:Belongs to the HSF family.,subcellular location:Cytoplasmic during normal growth and moves to the nucleus upon activation.,subunit:DNA-binding homotrimer in stressed or heat shocked cells, otherwise found as a homodimer.,
Protein name
Heat shock factor protein 2
Other name
HSF2; HSTF2; Heat shock factor protein 2; HSF 2; Heat shock transcription factor 2; HSTF 2
Human protein sequence Database
Q03933
Mouse protein sequence database
P38533
Rat protein sequence database
Cellular localization
Cytoplasm . Nucleus . Cytoplasmic during normal growth and moves to the nucleus upon activation.
Tissue expression
Bladder,Brain,PCR rescued clones,Testis,
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