Molecular weight (DA)
71kD
Immunogen
The antiserum was produced against synthesized peptide derived from human ZNF147. AA range:201-250
Specificity
EFP Polyclonal Antibody detects endogenous levels of EFP protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/10000.. IF 1:50-200
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq, Jul 2008],
Function
function:Mediates estrogen action in various target organs.,similarity:Contains 1 B30.2/SPRY domain.,similarity:Contains 1 RING-type zinc finger.,tissue specificity:Ubiquitous.,
Protein name
E3 ubiquitin/ISG15 ligase TRIM25
Other name
TRIM25; EFP; RNF147; ZNF147; E3 ubiquitin/ISG15 ligase TRIM25; Estrogen-responsive finger protein; RING finger protein 147; Tripartite motif-containing protein 25; Ubiquitin/ISG15-conjugating enzyme TRIM25; Zinc finger protein 147
Fields
>>NF-kappa B signaling pathway;>>RIG-I-like receptor signaling pathway;>>Influenza A
Human protein sequence Database
Q14258
Mouse protein sequence database
Q61510
Rat protein sequence database
Cellular localization
Cytoplasm . Cytoplasm, Stress granule . Nucleus .
Tissue expression
Expressed in breast tumors (at protein level). Ubiquitous.
Contract Us
Follow Us
Location： 
Specification
成功添加到购物车