Molecular weight (DA)
40kD
Immunogen
The antiserum was produced against synthesized peptide derived from human APOBEC4. AA range:309-358
Specificity
APOBEC4 Polyclonal Antibody detects endogenous levels of APOBEC4 protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. [provided by RefSeq, Jul 2008],
Function
cofactor:Zinc.,function:Putative C to U editing enzyme whose physiological substrate is not yet known.,similarity:Belongs to the cytidine and deoxycytidylate deaminase family.,tissue specificity:Predominantly expressed in testis.,
Protein name
Putative C->U-editing enzyme APOBEC-4
Other name
APOBEC4; C1orf169; Putative C->U-editing enzyme APOBEC-4; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4
Human protein sequence Database
Q8WW27
Mouse protein sequence database
Q497M3
Rat protein sequence database
Tissue expression
Predominantly expressed in testis.
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