Molecular weight (DA)
68kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC5A6. AA range:551-600
Specificity
SMVT Polyclonal Antibody detects endogenous levels of SMVT protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
function:Transports pantothenate, biotin and lipoate in the presence of sodium.,similarity:Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.,
Function
function:Transports pantothenate, biotin and lipoate in the presence of sodium.,similarity:Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.,
Protein name
Sodium-dependent multivitamin transporter
Other name
SLC5A6; SMVT; Sodium-dependent multivitamin transporter; Na(+)-dependent multivitamin transporter; Solute carrier family 5 member 6
Fields
>>Vitamin digestion and absorption
Human protein sequence Database
Q9Y289
Mouse protein sequence database
Q5U4D8
Rat protein sequence database
Cellular localization
Cell membrane ; Multi-pass membrane protein .; Cell membrane ; Multi-pass membrane protein . (Microbial infection) Exposure to E.coli lipopolysaccharides leeds to reduced cell membrane localization. .
Tissue expression
Expressed in microvessels of the brain (at protein level) (PubMed:25809983). Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas (PubMed:10329687).