Molecular weight (DA)
35kD
Immunogen
The antiserum was produced against synthesized peptide derived from human SLC25A11. AA range:132-181
Specificity
OGCP Polyclonal Antibody detects endogenous levels of OGCP protein.
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Dilution rate
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Purification process (Immunogen)
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Background
The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).[supplied by OMIM, Jan 2011],
Function
function:Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,
Protein name
Mitochondrial 2-oxoglutarate/malate carrier protein
Other name
SLC25A11; SLC20A4; Mitochondrial 2-oxoglutarate/malate carrier protein; OGCP; Solute carrier family 25 member 11
Human protein sequence Database
Q02978
Mouse protein sequence database
Q9CR62
Rat protein sequence database
P97700
Cellular localization
Mitochondrion inner membrane ; Multi-pass membrane protein .
Tissue expression
B-cell lymphoma,Brain,Muscle,Tongue,Uterus,
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